Aacrjournals.org

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Site specification: IP Number of site Aacrjournals.org is 171.66.121.222. Location is United States. Description: Since the passage of the National Cancer Act in 1971, research has steadily developed and improved therapeutic approaches to combat cancer. We have seen the development of targeted drugs with fewer side effects that block the malfunctions that drive cancer cells to proliferate out of control. There is still a need to increase the success rates of drugs transitioning from one phase to the next. With Guest Editors, Drs. Susan Bates and Giusepe Giaccone, this CCR Focus illustrates lessons learned in drug development through specific examples and highlight strategies for success., keywords:American Association for Cancer Research,AACR,Journals,journal,articles,papers,publications,manuscript,submit,submission system,SmartSubmit,Impact Factor,cited,citations,OnlineFirst,published ahead of print,Author Services Center,High-Impact Science,CCR Focus Archive,Centennial Series Reviews,Meeting Abstracts Online,CR Magazine,Meeting Reports,AACR Education Book,Cancer Medicine 8,Information for Author,Editors,Reviewers,Readers,Subscribers,Librarians,Advertisers,Cancer Research,CanRes,Clinical Cancer Research,CCR,Cancer Epidemiology,Biomarkers & Prevention,CEBP,Molecular Cancer Research,MCR,Molecular Cancer Therapeutics,MCT,Cancer Prevention Research,CaPR,Cancer Discovery,New Issue,CCR Focus,DNA Repair,growing understanding,mutational complexity,most solid tumors,clear that DNA will remain,among most important therapeutic targets,foreseeable future,point reinforced recent months,by clinical data showing activity,PARP inhibitors,breast cancer,patients BRCA1 loss,important gene,homologous recombination,double-strand break,DNA repair pathway,September 15th issue,aimed at increasing comprehension,more translational aspects,DNA repair,CCR Focus Archives.

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